Xiaoli Guo

Dr. Xiaoli Guo is an Associate Professor of Biomedical Engineering. She received her Ph.D. degrees in Biomedical Engineering from Shanghai Jiao Tong University in 2008, and then worked as an Assistant Professor. Her research interests include neural plasticity and rehabilitation after neural injury, such as stroke, amputation and Parkinson's Disease. 

Education

PhD in Biomedical Engineering (2003.09-2008.01), School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China
BS in Biomedical Engineering (1999.09-2003.07), School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China



Work experience
Associate Professor (2019.01 – Present)

     School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China

Assistant Professor (2011.04 – 2018.12)
     School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China

Assistant Professor (2008.08 – 2011.03)
     Department of Biomedical Engineering, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China


Visit and work experience

Visiting Scholar (2014.09 – 2015.08) 
Central Institute of Mental Health, Heidelberg University, Germany 



Research

Brain plasticity and rehabilitation based on neuroimaging and neural signal analysis

Research Project


1. 1/2018 – 12/2021  National Nature Science Foundation of China (PI: Guo XL)

Mechanism of motor imagery for stroke rehabilitation using analysis of dynamic brain networks from EEG source signals, RMB 620,000 yuan

2. 5/2017 – 4/2020   Nature Science Foundation of Shanghai (PI: Guo XL)

Topological analysis of dynamic brain networks during meditation, RMB 200,000 yuan

3. 1/2011 – 12/2013  National Nature Science Foundation of China (PI: Guo XL)

Plasticity of cortical neural network following ischemic stroke and its recovery, RMB 240,000 yuan



Monograph

1.    Li Ding, Kexu Zhang, Xu Wang, Shanbao Tong, Xiaoli Guo*, Jie Jia*, Functional reorganization of white matter supporting the transhemispheric mechanism of mirror therapy after stroke: a multimodal MRI study. IEEE Transactions on Neural Systems and Rehabilitation Engineering. 2025.

2.    Kexu Zhang, Li Ding, Xu Wang, Jinyang Zhuang, Shanbao Tong, Jie Jia*, Xiaoli Guo*, Mirror Therapy Reduces Excessive Variability of Motor Network in Stroke Patients: a randomized controlled trial. European Journal of Physical and Rehabilitation Medicine. 2025.

3.     Jinyang Zhuang, Xiyuan Lei, Xiaoli Guo, Li Ding, Jie Jia*, Motor and parietal cortex activity responses to mirror visual feedback in patients with subacute stroke: An EEG study. Clinical Neurophysiology Practice. 2024, 10: 12-21.

4.    Li Ding, Dan Wang, Chengcheng Wu, Xu Wang, Jinyang Zhuang, Xiaoli Guo*, Jie Jia*, Electrophysiological Evidence on Mirror Therapy for Promoting Perceptuo-Motor Processes in Stroke Patients. IEEE Transactions on Neural Systems and Rehabilitation Engineering. 2024, 32: 4197-4206.

5.    Yamin Li, Saishuang Wu, Jiayang Xu, Haiwa Wang, Qi Zhu, Wen Shi, Yue Fang, Fan Jiang, Shanbao Tong, Yunting Zhang*, Xiaoli Guo*, Interbrain substrates of role switching during mother–child interaction. Human Brain Mapping, 2024, 45(5): e26672.

6.    Kexu Zhang, Li Ding, Xu Wang, Jinyang Zhuang, Shanbao Tong, Jie Jia*, Xiaoli Guo*, Evidence of mirror therapy for recruitment of ipsilateral motor pathways in stroke recovery: A resting fMRI study. Neurotherapeutics, 2024, 21(2): e00320.

7.    Xiaoli Guo, Shuyuan Zhao, Lingxiao Yu, He Wang, Mirabel Ewura Esi Acquah, Wei Chen, Dongyun Gu, Neural correlates of abnormal cortical gait control in Parkinson's disease: a whole-gait-cycle EEG study, IEEE Transactions on Biomedical Engineering, 2024, 71(2): 400-409.

8.    Kexu Zhang, Hewei Wang, Xu Wang, Xin Xiong, Shanbao Tong, Changhui Sun, Bing Zhu, Yiming Xu, Mingxia Fan, Limin Sun*, Xiaoli Guo*. Neuroimaging prognostic factors for treatment response to motor imagery training after stroke. Cerebral Cortex, 2023, 33, 9504-9513.

9.     Kexu Zhang, Chaowei Wu, Yuanyuan Lyu, Jianbo Xiang, Changjie Pan, Xiaoli Guo*, Shanbao Tong*, Upper-Limb Amputation Disrupts the Interhemispheric Structural Rather than Functional Connectivity, Brain Connectivity, 2023, 13(3):133-142.

10.  Hewei Wang, Xin Xiong, Kexu Zhang, Xu Wang, Changhui Sun, Bing Zhu, Yiming Xu, Mingxia Fan, Shanbao Tong, Xiaoli Guo*, Limin Sun*, Motor network reorganization after motor imagery training in stroke patients with moderate to severe upper limb impairment, CNS Neuroscience & Therapeutics, 2023, 29(2):619-632. 

11.  Jiaqi Wang, Xiaoli Guo, Ziping Xing, Guanghai Wang, Jingyi Wang, Jingyi Hu, Junfeng Sun, Chunbo Li, Shanbao Tong, Xiangfei Hong, EEG correlates of anticipatory attention and target processing in children and adults during visual spatial attention, Physiology & Behavior, 2023, 271:114341.

12.  Xiaoli Guo, Meiyun Wang, Xu Wang, Menglin Guo, Ting Xue, Zhuo Wang, Han Li, Tianjiao Xu, Bin He, Donghong Cui and Shanbao Tong, Progressive Increase of High-Frequency EEG Oscillations during Meditation is Associated with its Trait Effects on Heart Rate and Proteomics: A Study on the Tibetan Buddhist, Cerebral Cortex. 2022, 32(18): 3865-3877.

13.  Xiaoli Guo, Xiaoying Zhang, Meng Sun, Lingxiao Yu, Chuan Qian, Jidan Zhang, Wenli Xu, Yu Xie, Tao Xu, Zheng Jin, Modulation of Brain Rhythm Oscillations by Xingnao Kaiqiao Acupuncture Correlates with Stroke Recovery: A Randomized Control Trial, Journal of Complementary Medicine. 2022, 28(5): 436-444.

14.  Tianhong Zhang, Yingyu Yang, Lihua Xu, Xiaochen Tang, Yegang Hu, Xin Xiong, Yanyan Wei, Huiru Cui, Yingying Tang, Haichun Liu, Tao Chen, Zhi Liu, Li Hui, Chunbo Li, Xiaoli Guo*, Jijun Wang*, Inefficient Integration during Multiple Facial Processing in Pre-morbid and Early Phases of Psychosis, The World Journal of Biological Psychiatry. 2022, 23(5): 361-373.

15.  Ting Xue, Benjamin Chiao, Tianjiao Xu, Han Li, Kai Shi, Ying Cheng, Yuan Shi, Xiaoli Guo, Shanbao Tong, Menglin Guo, Soo Hong Chew, Richard P Ebstein, Donghong Cui, The heart-brain axis: A proteomics study of meditation on the cardiovascular system of Tibetan Monks, EBioMedicine. 2022, 80:104026.

16.  Jianan Wang, Hongping Wang, Haoyong Yu, Jiaqi Wang, Xiaoli Guo, Shanbao Tong, Yuqian Bao, Xiangfei Hong, Neural mechanisms of inhibitory control deficits in obesity revealed by P3 but not N2 event-related potential component, Appetite, 2022, 171:105908.

17.  Yuanyuan Lyu, Francesca Zidda, Stefan Radev, Hongcai Liu, Xiaoli Guo, Shanbao Tong, Herta Flor, Jamila Andoh, Gamma Band Oscillations Reflect Sensory and Affective Dimensions of Pain, Frontiers in Neurology. 2022, 12: 695187.

18.  Xiangfei Hong, You Chen, Jijun Wang, Yuan Shen, Qingwei Li, Binglei Zhao, Xiaoli Guo, Wei Feng, Wenyuan Wu, Chunbo Li, Effects of multi-domain cognitive training on working memory retrieval in older adults: behavioral and ERP evidence from a Chinese community study. Scientific Reports. 2021, 11:1207.

19.  Xu Wang, Xiaonan Liu, Zhuo Wang, Shanbao Tong, Zheng Jin*, Xiaoli Guo*, Different reorganizations of functional brain networks after first-ever and recurrent ischemic stroke. Brain Research. 2021, 1765:147494.

20.  Lingxiao Yu, Xu Wang, Yuanyuan Lyu, Li Ding, Jie Jia, Shanbao Tong*, Xiaoli Guo*, Electrophysiological Evidences for the Rotational Uncertainty Effect in the Hand Mental Rotation: An ERP and ERS/ERD Study. Neuroscience. 2020, 432 (2020): 205-215.

21.  Xu Wang, Hewei Wang, Xin Xiong, Changhui Sun, Bing Zhu, Yiming Xu, Mingxia Fan, Shanbao Tong, Limin Sun*, Xiaoli Guo*, Motor Imagery Training After Stroke Increases Slow-5 Oscillations and Functional Connectivity in the Ipsilesional Inferior Parietal Lobule. Neurorehabilitation and Neural Repair. 2020, 34(4): 321-332.



Teaching

Undergraduate Courses

Data Structures

Biomedical Design I

Neural Cognitive Experiments

Graduate Course

Biomedical Signal Processing


Honor Award

Excellent Teachers (2016), Shanghai Jiao Tong University

Contact

E-mail:meagle@sjtu.edu.cn

telephone:021-34208558

address:文选楼510室

website:http://nel.sjtu.edu.cn