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Chunfu Zhang Chunfu Zhang obtained his PhD degree in 2002 from Chinese Academy of Sciences (ACS). During the next two years, he became Assistant Professor/Associate Professor in Shanghai Institute of Applied Physics of CAS. In 2004, he joined German Cancer Research Center (DKFZ) as a guest scientist. In 2007, he conducted postdoctoral study in UT Southwestern Medical Center. He joined the Med-X Research Institute, Shanghai Jiao Tong University in 2008. Currently he is Professor in School of Biomedical Engineering, SJTU. He has published more than 100 peer-reviewed papers, including Advanced Science, ACS Nano, Cancer Research, Biomaterials, Radiology, Advanced Functional Materials, ACS Applied Materials & Interfaces. My research interests mainly focus on multimodal molecular imaging probes for tumor theranostics and nuclear medicine for early diagnosis of cancers. |
1. Developing novel molecular imaging probes for tumor theranostics.
2. Nuclear medicine for clinical translation.
5年内代表性论文：
1. Y1. Yifei Jiang, Huizhen Yang, Guoping Jia, Wangxi Hai, Rongyi Huang, Peng Wang, Min Zhang, Danni Li, Yizhou Chen, Xiao Li*, Biao Li*, Chunfu Zhang*. Ultrasmall Au10–12 Nanoclusters: A Novel Platform for 223 Ra-Targeted Tumor α-Therapy. Exploration, 2026; 6:70144.
2. 2. He Gao, Yifei Jiang, Ying Miao, Huizhen Yang, Guoping Jia, Xinyu Zhang Runhua Feng, Zhenggang Zhu, Wangxi Hai, Xiaozheng Zhang, Peng Wang, Min Zhang, Xiao Li*, Biao Li*, Chunfu Zhang*. A 68Ga/161Tb-labeled FAP-targeted radioligand for enhanced theranostics: Prolonged tumor retention and metastasis inhibition. Journal of Controlled Release 2026, 399, 115298.
3. 3. Guoping Jia, Huizhen Yang, Qinghe Wu, Yifei Jiang, He Gao, Xubo Wu, Zhiyuan Xie, Haizhen Jin, Jia Xu*, Chunfu Zhang*. Immunomodulator triptolide synergizes with black phosphorus nanosheets-mediated calcium overload for mild heat-potentiated cancer immunotherapy. Chemical Engineering Journal 2026, 547, 180969.
4. 4. Huizhen Yang, Liu Liu, Guoping Jia, He Gao, Wangxi Hai, Qinghe Wu, Jia Xu , Yifei Jiang*, Chunfu Zhang*. FAP-targeted gold nanocluster-mediated radioligand therapy in combination with TGF-βRI inhibition for tumor therapy. Biomaterials, 2027, 338, 124605.
5. J5. Junjie Shen, Guoping Jia, Qinghe Wu, Huizhen Yang, Yifei Jiang, Xubo Wu, Yimin Chai, Chunfu Zhang*, Jia Xu*. Black phosphorus nanosheets fortified with catalase to enhance Schwann cell responses for neural repair. Journal of Controlled Release 2025, 380, 579–598.
6. 6. Xubo Wu, Qinghe Wu, Mengfei Hou, Yifei Jiang, Meng Li, Guoping Jia, Huizhen Yang, Chunfu Zhang*. Regenerating Chemotherapeutics through Copper-Based Nanomedicine: Disrupting Protein Homeostasis for Enhanced Tumor Therapy. Advanced Healthcare Materials. 2024, 2401954.
7. 7. Yifei Jiang, Anqi Wang, Qinghe Wu, Guoping Jia, Wangxi Hai, Min Zhang, Biao Li, Chunfu Zhang*. 89Zr-Labeled pH-Responsive Gold Nanoclusters for Radiosensitization Therapy of Tumors. ACS Appl. Nano Mater. 2024, 7, 15325−15333.
8. 8. Guoping Jia, Qinghe Wu, Mengfei Hou, Yifei Jiang, Huizhen Yang, Meng Li, Xubo Wu, and Chunfu Zhang*. Ultrathin BSA-Stabilized Black Phosphorous Nanoreactor Boosts Mild-Temperature Photothermal Therapy Through Modulation of Cellular Self-Defense Fate. Advanced Healthcare Materials 2024, 13(31), 2402079.
9. 9. Mengfei Hou, Haiyang Su, Qinghe Wu, Wenshe Sun, Pengli Zhang, Yifei Jiang, Kun Qian * and Chunfu Zhang*. A Self-Enhancing Nanoreactor Reinforces Radioimmunotherapy by Reprogramming Nutrients and Redox Metabolisms. Advanced Functional Materials 2023, 33(16), 2212510.
10. 10. Meng Li, Mengfei Hou, Qinghe Wu, Yifei Jiang, Guoping Jia, Xubo Wu, and Chunfu Zhang*. Simultaneous Inhibition of Heat Shock Response and Autophagy with Bimetallic Mesoporous Nanoparticles to Enhance Mild-Temperature Photothermal Therapy. Small Structures 2023, 4(11), 2300132.
11. 11. Yifei Jiang, Qinghe Wu, Mengfei Hou, Wangxi Hai, Min Zhang, Biao Li, Chunfu Zhang*. pH-sensitive gold nanoclusters labeling with radiometallic nuclides for diagnosis and treatment of tumor. Materials Today Bio 2023,19, 100578.
12. 12. Qinghe Wu, You Zhang, Guoping Jia, Mengfei Hou, Yifei Jiang, Weijun Wei, Ping Liu, Gang Huang, Jianhua Zou, Jingjing Zhang, Wangxi Hai, Min Zhang, Biao Li, Xiaoyuan Chen*, Chunfu Zhang*. A sequential dual-locked strategy with pH-responsive activation of photosensitizers and precise Cerenkov radiation delivery for cancer theranostics. Nano Today 2023, 52, 101984.
13. 13. Feng Wang, Qinghe Wu, Guoping Jia, Lingchi Kong, Rongtai Zuo, Kai Feng, Mengfei Hou, Yimin Chai, Jia Xu,* Chunfu Zhang,* and Qinglin Kang*. Black Phosphorus/MnO2 Nanocomposite Disrupting Bacterial Thermotolerance for Efficient Mild-Temperature Photothermal Therapy. Advanced Science 2023, 2303911.
E-mail：cfzhang@sjtu.edu.cn
telephone：86-21-62933323
address：Med-X 南楼 425室
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