汤耀辉
长聘副教授,博士生导师,科技部国家重点研发计划首席青年科学家,2019年度中国卒中学会优秀科技工作者,2021年度上海市青年科技启明星(A类),2023年度上海市东方英才。于2014年获得上海交通大学生物医学工程学院博士学位。2014-2018年先后在德国马克思普朗克研究所、美国斯坦福大学从事博士后研究。2018年3月担任上海交通大学生物医学工程学院长聘教轨助理教授,同时担任Aging&Disease杂志副主编,Stroke and Vascular Neurology的Assistant Editor以及多本SCI杂志编委;担任 中国卒中协会脑血流与代谢分会委员、上海市衰老与退行性疾病学会血管衰老与心脏血管疾病分会委员和上海市实验动物学会教育培训和科普专业委员会,长期从事神经生物学和神经病学,特别是脑血管疾病的转化医学研究。目前主持国家重点研发计划“干细胞与转化研究”青年项目、国家自然科学基金、上海交通大学医工交叉重点基金等,在Nature Communications, Advanced Science, Nano Today, Advanced functional materials, Stroke,Journal of cerebral blood flow and metabolism,Stem Cell Reports等国际重要期刊上共发表SCI论文60余篇,总影响因子500余分,H-因子33,引用3700余次。
2005.9-2009.7 北京林业大学 学士
2009.9-2014.7 上海交通大学 博士
2014-2018年先后在德国马克思普朗克研究所、美国斯坦福大学从事博士后研究。现任上海交通大学生物医学工程学院长聘副教授,同时担任多本SCI杂志编委(Frontiers in cellular Neuroscience, Current stem cell research and therapy, ARC journal of neuroscience, Sciencematters等);长期从事神经生物学和神经病学,特别是脑血管疾病的转化医学研究。
2014.7-2015.9 德国马克斯普朗克研究所 博士后
2015.10-2018.2 美国斯坦福大学 博士后
2018.3-2022.6 上海交通大学 长聘教轨助理教授
2022.6-2023.12 上海交通大学 长聘教轨副教授
2024.1-至今 上海交通大学 长聘副教授
脑血管病的发病机制;胶质细胞在脑血管病中的作用;干细胞和外泌体治疗缺血性脑卒中;组织工程
主持基金项目:
1. 国家自然科学基金面上项目,2024/01-2027/12
2. 上海交通大学医工交叉重点基金,2023/01-2025/12
3. 上海市“科技创新行动计划”启明星项目(A类), 2021/07-2024/06
4. 国家自然科学基金面上项目,2021/01-2024/12
5. 国家重点研发计划重点专项青年项目, 2019/09-2024/12
6. 国家自然科学基金青年项目,2019/01-2021/12
7. 上海交通大学医工交叉重点基金,2019/01-2021/12
8. 上海交通大学医工交叉青年基金A,2019/01-2021/12
9. 上海交通大学医工交叉青年基金B,2019/01-2021/12
参与基金项目:
1. 上海市教育委员会科研创新计划项目,2019/01-2023/12
2. 国自然重点,2020/01-2024/12
1. Fengzhen Cui, Shiyu Deng, Yan Fu, Tongtong Xu, Shuangshuang Bao, Siyi Wang, Yahang Lin, Xianghui Wang, Faming Zhao, Tingting Zhang, Shunqing Xu, Zhijun Zhang, Wanlu Li, Guo-Yuan Yang, Huanwen Tang, Jixian Wang*, Xia Sheng*, Yaohui Tang*. (Co-corresponding author). Maternal phthalates exposure promotes neural stem cells differentiation into phagocytic astrocytes and synapse engulfment via IRE1α/XBP1s pathway. Cell Reports. 2025 Jan 2; 44(1):115126.
2. Xiaojing Shi#, Lu Zhang#, Shengju Wu#, Chunfu Zhang, Muyassar Mamtilahun, Yongfang Li, Zhijun Zhang, Changjing Zuo, Fengzhen Cui, Wanlu Li, Guo-Yuan Yang, Yaohui Tang*. A simple polydopamine-based platform for engineering extracellular vesicles with brain-targeting peptide and imaging probes to improve stroke outcome. Journal of Extracellular Vesicles. 2025; 14: e70031.
3. Xiaojing Shi#, Longlong Luo#, Jixian Wang#, Hui Shen, Yongfang Li, Muyassar Mamtilahun, Chang Liu, Rubing Shi, Joon Hyuk Lee, Hengli Tian, Zhijun Zhang, Yongting Wang, Won-Suk Chung*, Yaohui Tang*, and Guo-Yuan Yang*. (Co-corresponding author) Stroke subtype-dependent synapse elimination by reactive gliosis in mice. Nature Communications. 2021 Nov 26; 12(1):6943. 高被引论文
4. Tongtong Xu, Lin Gan, Wei Chen, Dandan Zheng, Hanlai Li, Shiyu Deng, Dongliang Qian, Tingting Gu, Qianyuan Lian, Gracie Shen, Qingzhu An, Wanlu Li, Zhijun Zhang, Guo-Yuan Yang, Huitong Ruan*, Wenguo Cui*, Yaohui Tang*. (Co-corresponding author). Bridging immune-neurovascular crosstalk via the immunomodulatory microspheres for promoting neural repair. Bioactive Materials. 2025; 44: 558–571
5. Fengzhen Cui, Qingfei Pan, Siyi Wang, Faming Zhao, Runxin Wang, Tingting Zhang, Yaying Song, Jun He, Haolin Zhang, Qiang Weng, Yang Jin, Wei Xia, Yuanyuan Li, Guo-Yuan Yang, Winnok De Vos, Jean-Pierre Timmermans, Shunqing Xu*, Yaohui Tang* and Xia Sheng*. (Co-corresponding author) Maternal benzophenone exposure impairs hippocampus development and cognitive function in mouse offspring. Advanced Science, 2021: e2102686. (IF: 17.521)
6. Shiyi Zhou#, Chang Liu#, Jixian Wang#, Jing Ye#, Qianyuan Lian, Lin Gan, Shiyu Deng, Tongtong Xu, Yiyan Guo, Wanlu Li, Zhijun Zhang, Guo-Yuan Yang and Yaohui Tang*. CCL5 mediated astrocyte-T cell interaction disrupts the blood-brain barrier in mice after hemorrhagic stroke.Journal of Cerebral Blood Flow & Metabolism, 2024, 44(3), 367–383.
7. Yixu Jiang#, Ruiqi Wang#, Cheng Wang, Yiyan Guo, Tongtong Xu, Zhijun Zhang, Guo-Yuan Yang, He Xu*, Yaohui Tang*. (Co-corresponding author) Brain Microenvironment Responsive and Pro-angiogenic Extracellular Vesicle-Hydrogel for Promoting Neurobehavioral Recovery in Type 2 Diabetic Mice after Stroke. Advanced Healthcare Materials. 2022 Sep 7;e2201150.
8. Cheng Wang#, Xuewei Yang#, Yixu Jiang, Lin Qi, Deli Zhuge, Tongtong Xu, Yiyan Guo, Mingwu Deng, Wenjie Zhang, Dongyan Tian, Qingqing Yin, Li Li, Zhijun Zhang, Yongting Wang, Guo-yuan Yang, Yijie Chen*, Yaohui Tang*. (Co-corresponding author) Targeted Delivery of Fat Extract by Platelet Membrane-Cloaked Nanocarriers for the Treatment of Ischemic Stroke. Journal of Nanobiotechnology. 2022 May 31;20(1):249. (IF:10.435)
9. Huitong Ruan#, Yongfang Li#, Cheng Wang, Yixu Jiang, Yulong Han, Yiwei Li, Dandan Zheng, Jing Ye, Gang Chen, Guo-yuan Yang, Lianfu Deng, Ming Guo, Xingcai Zhang*, Yaohui Tang*, Wenguo Cui*. (Co-corresponding author) Click Chemistry Extracellular Vesicle /Peptide/Chemokine Nanomissiles for Treating CNS Injuries. Acta Pharmaceutica Sinica B. 2023 May; 13 (5), 2202-2218. (IF:14.903)
10. Yaying Song, Zongwei Li, Tingting He, Meijie Qu, Lu Jiang, Wanlu Li, Xiaojing Shi, Jiaji Pan, Linyuan Zhang, Yongting Wang, Zhijun Zhang*, Yaohui Tang* and Guo-Yuan Yang*. (Co-corresponding author) M2 microglia-derived exosomes protect the mousebrain from ischemia-reperfusion injury via exosomalmiR-124. Theranostics. 2019; 9(10):2910-2923. (IF:11.6) 高被引论文
生物学导论,32学时,本科生
神经生物学实验基础,32学时,研究生
学术报告会,32学时,研究生
2023-至今 Aging and disease 副主编
2022.7-至今 Stroke and Vascular Neurology Assistant Editor
2016.7 - 至今 Frontiers in cellular neuroscience 编委
2019.11- 至今 Current Stem Cell Research & Therapy 编委
2019.6
- 至今 中国卒中协会脑血流与代谢分会 委员
2019.10- 至今 上海市实验动物学会教育培训和科普专业委员会 委员
2019. Stroke conference, Early Career Investigator Award
Brain 2019 Young Investigator award
2019年度中国卒中学会优秀科技工作者
2020 上海市青年科技启明星(A类)
2023年度上海市东方英才(青年项目)
邮箱地址:yaohuitang@sjtu.edu.cn
办公地址:教三楼 211室
网址:https://www.x-mol.com/groups/tangyaohui