林俐
长聘教轨助理教授,博导。于上海交通大学生物医学工程学院获学士和博士学位;之后分别在上海交大和伊利诺伊大学香槟分校开展博士后研究。在Adv Sci, Small Methods, Nano Lett, ACS Nano等期刊上发表高水平论文,被引1100余次,担任多个SCI期刊(包括IEEE, ACS, Elsevier, SpringerNature 等出版社期刊)的审稿人、Exploration青年编委。曾获SERS国际会议最佳墙报奖、IMCO国际会议最佳论文奖等。博士期间开发高灵敏缝隙增强拉曼探针,并帮助实现大规模生产,有望临床转化成为首个拉曼造影剂。近年来的研究兴趣集中在基于光学方法的无创病灶定位和重建,包括拉曼响应纳米探针的设计开发、深穿透拉曼光谱技术和拉曼光学图像重建。开发活体透射拉曼光谱技术,实现了深穿透检测、定位和成像等一系列研究。
欢迎生医工、光学、化学和材料领域的硕士、博士加入课题组!欢迎对科研感兴趣的本科生提前加入实验室。近年多次指导国自然基金青年学生项目、本科生挑战杯项目、毕业设计、国家级大创(入选国创年会展示)。可直接Email 联系我。
招生:2025入学的博士、硕士名额各1。希望招收具有化学/材料/AI/生信背景的博士研究生。
基于深穿透光谱技术的活体无创光学成像
基于拉曼光谱的肿瘤快速诊断及预后分析
等离激元金属纳米基底及探针溶胶的设计与开发
Featued Articles After 2021
1. Binge Deng, Yan Wang, Xiangdong Bu, Jin Li, Jingsong Lu, Linley Li Lin*, Yaohui Wang*, Yao Chen*, Jian Ye*. Sentinel lymph node identification using NIR-II ultrabright Raman nanotags on preclinical models. Biomaterials, 2024, 308, 122538. (IF=12)
2. Shiyan Fang, Siyi Wu, Zhou Chen, Chang He, Linley Li Lin*, and Jian Ye*. Recent progress and applications of Raman spectrum denoising algorithms in chemical and biological analyses: A review. Trends in Analytical Chemistry, 2024, 172, 117578. (IF=13.1)
3. Haoqiang Xie, Yumin Zhang, Zongyu Wu, Zhouzhou Bao*, Li Lin*, and Jian Ye*. Locating Three-Dimensional Position of Deep-Seated SERS Phantom Lesions in Thick Tissues Using Tomographic Transmission Raman Spectroscopy. ACS Applied Materials & Interfaces, 2023, 15, 38, 44665-44675. (IF=9)
4. Li Lin*, Haoqi He, Ruiyang Xue, Yumin Zhang, Ziwen Wang, Shuming Nie*, Jian Ye*. Direct and quantitative assessments of near‑infrared light attenuation and spectroscopic detection depth in biological tissues using surface‑enhanced Raman scattering. Med-X, 2023, 1, 9.
5. Zongyu Wu, Binge Deng, Yutong Zhou, Haoqiang Xie, Yumin Zhang, Li Lin*, Jian Ye*. Non-invasive detection, precise localization, and perioperative navigation of in vivo deep lesions using transmission Raman spectroscopy. Advanced Science. 202301721. (IF=17.2)
6. Yumin Zhang, Li Lin*, Jian Ye*. A rapid and universal method for depth estimation of lesions in heterogeneous tissues via photosafe ratiometric transmission Raman spectroscopy. View, 2023, 20230022. (IF=8.6)
7. Yumin Zhang, Ruoyu Chen, Fugang Liu, Peng Miao, Li Lin*, and Jian Ye*. In Vivo Surface-Enhanced Transmission Raman Spectroscopy under Maximum Permissible Exposure: Toward Photosafe Detection of Deep-Seated Tumors. Small Methods, 2023, 7(2), 2201334. (IF=15.2)
8. Li Lin, Ruiyang Xue, Shuming Nie. "Surface-enhanced Raman scattering (SERS) nanoparticles for biodiagnostics, bioimaging, and spectroscopy-guided cancer surgery", In: Reference Module in Materials Science and Materials Engineering, Elsevier, 2022. (Invited Book Chapter)
9. Haoqi He, Yumin Zhang, Shuo Zhu, Jian Ye*, and Li Lin*. "Resonant strategy in designing NIR-II SERS nanotags: a quantitative study." The Journal of Physical Chemistry C, 2022, 126, 12575. (IF=4.2)
10. Yao Lu, Li Lin*, Jian Ye*, “Human metabolite detection by surface-enhanced Raman spectroscopy”, Materials Today Bio, 2022, 13, 100205. (IF=10.5)
Featured Articles Before 2021
1. Yuqing Gu, Chang He, Yuqing Zhang, Li Lin, Benjamin David Thackray, Jian Ye*, “Gap-enhanced Raman tags for physically unclonable anticounterfeiting labels”, Nature Communications, 2020, 11, 516. (IF=13.8)
2. Li Lin, Qiang Zhang, Xiyao Li, Meng Qiu, Xin Jiang, Hongchen Gu*, Dang Yuan Lei*, Jian Ye*, “Electron Transfer in Plasmonic Nanogaps Interrogated with Surface-Enhanced Raman Scattering,” ACS Nano, 2018, 12, 6492. (IF=15.8)
3. Li Lin, Zhonghui Liu, Xiyao Li, Hongchen Gu, Jian Ye*, “Quantifying the Reflective Index of Nanometer-Thick Molecular Layers on Nanoparticle,” Nanoscale, 2017, 9, 2213. (IF=7.2)
4. Li Lin, Mario Zapata, Min Xiong, Zhonghui Liu, Shanshan Wang, Hong Xu, Andrei G. Borisov, Hongchen Gu, Peter Nordlander*, Javier Aizpurua*, Jian Ye*, “Nanooptics of Plasmonic Nanomatryoshkas: Shrinking the Size of a Core–Shell junction to Subnanometer,” Nano Letters, 2015, 15, 6419. (IF=11.1)
纳米材料光谱学的生物医学应用,春季学期
学术规范与科研伦理(英文课程),秋季学期医学工程的伦理及学术规范(面向医工方向博士),春季学期
生物医学工程学术前沿(面向医工方向博士),春季学期
邮箱地址:linli92@sjtu.edu.cn
办公地址:Med-X 207室
网址:http://www.yelab.sjtu.edu.cn/html/cn/index.php?ac=article&at=list&tid=3